Its theme's rank, 14 days: 2 on the Claude Code sheet
47 people reported

All time, since Sep 15, including 3 thumbs-up on GitHub.

Safeguards block requests

“wrong safeguards flagged for biology research”

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I hit this bug: rapsheet.dev/sheets/claude-code/issues/3603/file
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Fading. 4 reports and thumbs-up in the last 7 days and 6 the week before, down from 12 a week at the late-September peak. Not fixed, and no vendor reply yet.

Safeguards flag sessions and block responses to requests. Claude Code shows an API error that "safeguards flagged this session" with a Details tag such as [bio]; rewriting the prompt did not change anything.

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Where
API client
Error text
API Error: Opus 5.5's safeguards flagged this session (https://www.anthropic.com/legal/aup).
Versions
2.1.272 to 2.1.314
Platforms
Linux, macOS, Windows
How bad
Breaks a normal workflow.

Part of: Safeguards block session requests34 bugs

  1. Cyber safeguard blocks sessions377 people
  2. Reasoning_extraction safeguard block134 people
  3. Cyber safeguard pauses sessions52 people
  4. Safeguards refuse work requests48 people
  5. Classifier halts routine replies12 people
  6. Requests blocked with a [cyber] flag8 people
  7. Refusal on own-code hardening11 people
  8. SSH to own devices refused7 people
  9. Pentest work blocked6 people
  10. CTF requests flagged as malicious6 people
Show all 33Show only the largest 10
  1. Classifier blocks own-project work6 people
  2. Classifier halts reverse engineering5 people
  3. Safeguards flag verified cyber work6 people
  4. Firmware requests flagged as cyber6 people
  5. Classifier stops benign replies5 people
  6. reasoning_extraction API error5 people
  7. Safeguard blocks all messages4 people
  8. [bio] classifier blocks responses4 people
  9. Reasoning extraction safeguard block4 people
  10. Security investigation requests blocked3 people
  11. Classifier stops DeFi bot work3 people
  12. Safeguards block CVP members3 people
  13. "[cyber]" flag stops sessions1 person
  14. Safety classifier blocks agent3 people
  15. Fictional hacking content flagged3 people
  16. Cyber verification prompt recurs2 people
  17. Cyber safeguards block own devices2 people
  18. Safety classifier stops auth work2 people
  19. Phishing research project flagged2 people
  20. Cyber stop on report tasks2 people
  21. Cyber safety block on audits2 people
  22. Biological safeguard triggers in sessions with no biology content2 people
  23. Unexpected safeguards notice2 people

Original reports46, newest first

  1. False positive: safety filter blocked a genomics ML brainstorm#107167
  2. API Error: Sonnet 5 Refused Request Citing AUP (bio)#107028
  3. False positive refusal on DRT2 bacterial defense system research question#106776
  4. Biosafety Classifier Too Sensitive, Flags Benign Requests#106283
  5. Biosafety classifier too sensitive, flags benign requests#106282
  6. Request Blocked for Local Web Vulnerability Scanning#106097
  7. Request incorrectly flagged for "Bio" content while building Discord bot API integration#106009
  8. Safeguards incorrectly flag legitimate biology research requests#105897
  9. Safety classifier halted a Write call summarizing a public drug-development blog post, with no reason given; /feedback also rejected#105585
  10. Bug Report: blocked by the bio guardrail#103627
Show all 46Show only the newest 10
  1. Opus 5.5 Safeguard False Positive [bio] on Science Education Video Task#103522
  2. Opus 5.5 Over-Triggers Safeguard on Graduate Molecular Toxicology Content#103430
  3. False-Positive [bio] Safeguard Silently Downgrades Opus 5.5 to Opus 5#103382
  4. Opus 5.5 [bio] safeguard false positives on routine life-sciences literature work, sharp increase since 2026-10-16#103049
  5. Refuses to test security vulnerability locally#102051
  6. Prompt classifier incorrectly blocks valid prompt#101795
  7. Opus 5.5 [bio] classifier interrupts benign biomedical literature work (reading published papers, pre-commit secret scan)#101274
  8. Opus 5.5 [bio] classifier flags benign in-silico protein-engineering session; blocks file-listing output and /feedback returns 403#101211
  9. [bio] safeguard blocks fantasy world-building session with no biology content#101086
  10. [bio] safeguard false positives repeatedly halt a protein-design session (76 flags, 40 request IDs); the stall is also misreported to the agent#100552
  11. Anthropic API: Excessive false positive safety flags on medical content#100352
  12. Anthropic API Error: Overly restrictive content filter on harmless bioinformatics operations#100287
  13. false-positive na "cybersecurity" promt to siema masz...#100015
  14. Unclear error flagging on present-tense capability questions#99963
  15. Local Project Application Violation Error#99601
  16. Inaccurate [bio] safety flag regarding legitimate university work making me unable to use Claude Code#99253
  17. Claude API Security Filter Triggering on Local SQL Injection Tests#99097
  18. Safeguards prevent testing of locally running applications#99061
  19. Overly restrictive content filtering for legitimate cancer research queries#98698
  20. Incorrect Content Policy Flagging: Open Source Library Wrapper Marked as "bio"#98602
  21. Anthropic API Error: Conversation Blocked by Biohazard Safeguards with Opus 5.5 and Sonnet 5.5#98346
  22. Classifier falsely flagging previously valid inputs#97700
  23. Safeguard triggers on local device testing#97351
  24. False Positive: Content Incorrectly Flagged#97277
  25. Anthropic API Error: Opus 5.5 safeguards incorrectly flagging legitimate biology research#96924
  26. classifier triggering on sending a '.' to wake claude after an api error.#96851
  27. False positive flagging without clear error context#96777
  28. Session terminated with incorrect [bio] reason outside biology context#96730
  29. False Positive Prompt Flagging#96593
  30. Session paused with [bio] flag during legitimate metabolic modeling research#96457
  31. CVP Integration Fails Against Local Vulnerable Test Instances#96376
  32. Opus 5.5 refuses to summarize conversation, cites biology flag, suggests switching models#96275
  33. Model refuses to engage with biological/biotech content in CRUD delivery simulation tasks#95704
  34. False positive [bio] safeguard trigger on routine RNA-seq statistical analysis#95700
  35. Anthropic API Error: Model refuses request with vague "bio" classification#94693
  36. Anthropic API Error: Unexpected Refusal on Valid Request#94544

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